Rona- Your point about knowing what questions were raised is so important! It is difficult to get a protocol in final form. As you mentioned, it is still important to engage local community about the protocol, even if the study is not being conducted at your site. Understanding the questions and concerns raised by the community as well as the steps taken to incorporate those concerns or reasons why changes could not be made, are crucial to maintaining trust in the community. As you mentioned this communication can help develop messages and communication strategies about the trial.  It can also help shape the plans for results dissemination or feed into the issues management plan!