What implications did the lack of inclusion of clean needles in the prevention package have for trial results?
Although there is a controversial element in this case, evidence of PrEP efficacy among injection drug users could probably be demonstrated earlier, as the number of new HIV infections, needed to draw a conclusion on efficiency, would have been reached sooner. In the end, less study participants may need to be exposed to an experimental method. The sooner the effectiveness can be confirmed, the sooner the new method of prevention can be rolled out at a national/ global scale. It would be interesting to make a statistical analysis of this scenario: How many people would be exposed to an experimental method without additional intervention (in this case clean needles), and how many study participants would need to be exposed with additional intervention?
