I appreciate and respects all the comments from my colleagues. This is an interesting study in that clean needles were not provided to the study participants.This could be explained by the Thailand government on drug users.The provision of clean needles is a contentious issue where a solid universal position have never been attained due to the various country context.It may sound unethical not to provide needles but it also mirror the true real life happenings.The study results cannot be ignored but am not sure what analysis was conduct whether it is intent to treat or per protocol analysis.
This study also suggest that stakeholders were not properly involved.Researchers need to involve also stakeholders in designing a comprehensive HIV prevention package.This therefore calls for empowerment efforts among the various stakeholders to inform a trial.The researcher is obligated to report both the negative and positive outcomes of a trial.


